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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 2
1996 4
1997 16
1998 9
1999 17
2000 13
2001 12
2002 15
2003 16
2004 7
2005 11
2006 13
2007 15
2008 11
2009 17
2010 24
2011 23
2012 16
2013 26
2014 24
2015 27
2016 27
2017 28
2018 35
2019 28
2020 34
2021 41
2022 24
2023 31
2024 12

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529 results

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Page 1
The noncanonical NF-κB pathway.
Sun SC. Sun SC. Immunol Rev. 2012 Mar;246(1):125-40. doi: 10.1111/j.1600-065X.2011.01088.x. Immunol Rev. 2012. PMID: 22435551 Free PMC article. Review.
Under normal conditions, NIK is targeted for continuous degradation by a tumor necrosis factor (TNF) receptor-associated factor-3 (TRAF3)-dependent E3 ubiquitin ligase. ...
Under normal conditions, NIK is targeted for continuous degradation by a tumor necrosis factor (TNF) receptor-associated …
TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells.
Whillock AL, Ybarra TK, Bishop GA. Whillock AL, et al. J Biol Chem. 2021 Jan-Jun;296:100465. doi: 10.1016/j.jbc.2021.100465. Epub 2021 Feb 25. J Biol Chem. 2021. PMID: 33639170 Free PMC article.
Highlighting the role of TRAF3 as a tumor suppressor, loss-of-function TRAF3 mutations are associated with human B-cell malignancies, while B-cell-specific deletion of TRAF3 in mice leads to autoimmunity and lymphoma development. ...
Highlighting the role of TRAF3 as a tumor suppressor, loss-of-function TRAF3 mutations are associated with human B-cell malignancies, …
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Li J, Yao Z, Liu X, Duan R, Yi X, Ayoub A, Sanders JO, Mesfin A, Xing L, Boyce BF. Li J, et al. Nat Commun. 2023 Jan 11;14(1):159. doi: 10.1038/s41467-023-35801-z. Nat Commun. 2023. PMID: 36631487 Free PMC article.
TGFbeta1 induces age-related bone loss by promoting degradation of TNF receptor-associated factor 3 (TRAF3), levels of which decrease in murine and human bone during aging. ...
TGFbeta1 induces age-related bone loss by promoting degradation of TNF receptor-associated factor 3 (TRAF …
TNF receptor-related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF-κB-inducing kinase-mediated hepatocyte transdifferentiation.
Shiode Y, Kodama T, Shigeno S, Murai K, Tanaka S, Newberg JY, Kondo J, Kobayashi S, Yamada R, Hikita H, Sakamori R, Suemizu H, Tatsumi T, Eguchi H, Jenkins NA, Copeland NG, Takehara T. Shiode Y, et al. Hepatology. 2023 Feb 1;77(2):395-410. doi: 10.1002/hep.32317. Epub 2022 Feb 1. Hepatology. 2023. PMID: 34995376 Free PMC article.
Intrahepatic NIK levels were elevated in liver-specific Traf3 -deficient and Pten -deficient mice, and NIK inhibition alleviated cholangiocyte overgrowth. In human ICCs, we identified an inverse correlation between TRAF3 and NIK expression, with low TRAF3 or high NIK expre …
Intrahepatic NIK levels were elevated in liver-specific Traf3 -deficient and Pten -deficient mice, and NIK inhibition alleviated cholangiocy …
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Zheng W, Zhou Z, Rui Y, Ye R, Xia F, Guo F, Liu X, Su J, Lou M, Yu XF. Zheng W, et al. Signal Transduct Target Ther. 2023 Feb 24;8(1):79. doi: 10.1038/s41392-022-01287-2. Signal Transduct Target Ther. 2023. PMID: 36823147 Free PMC article.
Innate immunity represents one of the main host responses to viral infection.(1-3) STING (Stimulator of interferon genes), a crucial immune adapter functioning in host cells, mediates cGAS (Cyclic GMP-AMP Synthase) sensing of exogenous and endogenous DNA fragments and generates i …
Innate immunity represents one of the main host responses to viral infection.(1-3) STING (Stimulator of interferon genes), a crucial immune …
529 results